The regular teaching of chemistry began in 1857 whereas the independent department was established in 1879 and directed thereafter by several outstanding Hungarian scientist. Among others I. Bugarszky (1903-13) should be remembered for his work in discovering important principles in chemical thermodynamics. In his basement laboratory G. Hevesi made his first fundamental experiments in academic year 1916/17 using radioactive isotopes as tracers. He was awarded the Nobel Prize in 1943. In addition to their contribution to the medical chemistry G. Gróh (1913-33) and L. Urbányi (1943-57) developed the curriculum substantially and wrote modern text books. The building shared by the departments of chemistry and physiology gained its present architectural form after reconstructions in 1911, and was modernized in the early seventies.