Contents page of the issue April 2007



EQUINE

A. Nagy, S. J. Dyson: Role of scintigraphy in diagnosing orthopaedic injuries in horses. Part 2 / 195
G. Piccione, C. Giannetto, A. Costa, F. Fazio, G. Caola: Effects of high intensity exercise on serum electrolytes and protein in Thoroughbred horses / 208

RUMINANTS
Cs. Csorba, L. Kocsis, T. Abonyi, L. Bozzay, E. Tóth, L. Ózsvári: Practical experiences of use of OrbeSeal® teat sealant in combination with antibiotic dry cow therapy in a large-scale Holstein-Friesian commercial dairy herd / 214
V. Faigl – M. Keresztes – A. Márton – Z. Schneider – L. Korvin – S. Sándor –G. D. Novotniné – M. Árnyasi – M. Kulcsár – A. Jávor – S. Cseh – Gy. Huszenicza: Melatonin and photoperiodic treatments for the induction of ovarian cyclicity in small ruminants: physiological aspects and practice. A review / 219

PORCINE
K. Mester, T. Magyar: Atrophic rhinitis – is eradication feasible? An overview on the disease and case report / 231

SMALL ANIMALS
S. Peters: Hyperkeratosis of dogs sole – many causes exist / 239

PET ANIMALS
J. Gál, G. Csécsei: Hypoplasy of tail muscle fibers in a Madagascarian day gecko (Phelsuma madagascariensis kochi). Case report / 245

PHARMACOLOGY
D. Szécsényi, P. Vajdovich, T. Gaál: Role of pump proteins causing therapy resistance in different diseases Literature review. Part 1 /

JUBILEE
Professor János Tanyi is 70 years old (L. Visnyei) / 249

ACADEMIC REPORTS, 2007
Veterinary research in 2006 in the light of academic reports. Part 1 / 251

IN MEMORIAM
Miklós Altrichter (1951–2006) (I. Bogár) / 218
István Lázár (1931–2006) (I. Majoros) / 230

A. Nagy – S. J. Dyson:
ROLE OF SCINTIGRAPHY IN DIAGNOSING OTRHOPAEDIC INJURIES IN HORSES. PART 2

The principles of nuclear medicine and image acquisition were reviewed in Part 1. In Part 2 the phases of and indications for bone scintigraphy and principles of image interpretation are discussed, followed by a summary of common normal and abnormal findings in horses of different disciplines.

G. Piccione – C. Giannetto – A. Costa – F. Fazio – G. Caola:
EFFECTS OF HIGH INTENSITY EXERCISE ON SERUM ELECTROLYTES AND PROTEIN IN THOROUGHBRED HORSES

This study investigated the physiological responses of five clinically healthy and regularly trained Thoroughbred horses to exercise in a 1800 meters course. Venous blood samples were collected at rest, immediately after the race, following 30 and 60 min resting. The effects of race on venous acid-base balance, potassium, sodium, chloride, calcium, phosphorus, magnesium, total protein, albumin, and α1-, α2-, β- and γ-globulins, were investigated. Exercise had a significant effect on phosphorus, potassium, magnesium, chloride, sodium, calcium, total protein, albumin, α1- and α2-globulins levels. After the race a significant increase was recorded in the concentrations of the above-mentioned parameters. A significant linear correlation was found between values of albumin and calcium. During maximal exercise loading, changes in potassium, sodium and protein concentrations are due to acute shifts of fluid from the extracellular to the intracellular space, and returned to its basal values within 30 minutes after exercise. Changes of chloride levels likely depend on shift phenomena between intra- and extracellular compartment involving erythrocytes. During maximal exercise adrenergic stimulation induces PTH secretion, that might have influence on the changes of blood calcium, phosphorus and magnesium concentrations.

Cs. Csorba – L. Kocsis – T. Abonyi – L. Bozzay – E. Tóth – L. Ózsvári:
PRACTICAL EXPERIENCES OF USE OF ORBESEAL® TEAT SEALANT IN COMBINATION WITH ANTIBIOTIC DRY COW THERAPY IN A LARGE-SCALE HOLSTEIN-FRIESIAN COMMERCIAL DAIRY HERD

The authors compared the effectiveness of an antibiotic dry cow therapy (ADCT) to a combination of OrbeSeal® teat sealant and ADCT at dry off in the prevention of clinical mastitis during the early lactation periods in 240 cows (n=960 udder quarters) of a Hungarian large-scale commercial dairy herd. As a dry cow antibiotic, Albadry Plus® intramammary infusion was used in both the control and the experimental group. In the control group 552 quarters (138 cows) were examined, and so were 408 quarters (108 cows) in the group dried off with OrbeSeal® and Albadry Plus®. The almost one-year-long experiment closing in October 2006 showed that the ADCT with Orbeasel® had a significant effect on the incidence of clinical mastitis in 1–8 days-in-milk (DIM) (67% decrease; tx=2.21%, control=6.7%; P=0.001), between 9 to 100 DIM (54.9% decrease; tx=4.21%, control=9.78%; P=0.001), and overall in the early lactation periods (1–100 DIM; 59.85% decrease; tx=6.62%, control=16.49%; P<0.001). The cost-benefit analysis of the ADCT in combination with OrbeSeal showed that the extra cost of the teat sealant (1600 HUF per cow; 6.27 EUR) has been 1.5 times recovered already by the 100th day of milk production. The decrease in loss due to clinical mastitis (taking into account the costs of drugs and withdrawal milk only) was 2.407 HUF (9.44 EUR) less per average cow, from 4313 HUF (16.91 EUR) to 1906 (7.47 EUR), that is why, the cost-benefit ratio was 1.5. Thus, the treatment has yielded 807 HUF (3.16 EUR) profit per average cow.

V. Faigl – M. Keresztes – A. Márton – Z. Schneider – L. Korvin – S. Sándor –G. D. Novotniné – M. Árnyasi – M. Kulcsár – A. Jávor – S. Cseh – Gy. Huszenicza:
MELATONIN AND PHOTOPERIODIC TREATMENTS FOR THE INDUCTION OF OVARIAN CYCLICITY IN SMALL RUMINANTS: PHYSIOLOGICAL ASPECTS AND PRACTICE. LITERATURE REVIEW

Seasonality of reproduction in small ruminants is a special biological feature evolved under evolutionary pressure, which has direct effects on production. The authors review the role of light and melatonin in the regulation of this seasonal pattern. They delineate physiological aspects of seasonality, the phenomenon of melatonin receptor 1 (MT1) polymorhism, and current knowledge about MT1 allels as possible markers of reproductive seasonality. Eventually, they summarize achievements of influencing reproductive activity by the use of different forms of photoperiod and melatonin treatment.

K. Mester – T. Magyar:
ATROPHIC RHINITIS – IS ERADICATION FEASIBLE? AN OVERVIEW ON THE DISEASE AND CASE REPORT

Atrophic rhinitis (AR) of swine still remained a frequent ’trouble maker’ on many large, industrial type pig farms. The authors first give a short, practical overview on the current knowledge of AR, then describe a field observational study on a farrow-to-finish pig farm of 1,000 sows, where the evolution of the disease was followed up for about 10 years from heavy clinical symptoms until achieving AR free status.
The farm was repopulated in 1993 from a breeding herd with no clinical signs of AR, however, infected with toxigenic Pasteurella multocida. AR became the disease of the most significant economic impact on the farm within two years. Then a control strategy was implemented based on the vaccination of breeding stock accompanying with management improving steps and antimicrobial treatments in the farrowing unit. First, a multi-component bacterin vaccine (vaccine A) was used (Bordetella bronchiseptica, P. multocida, Escherichia coli and erysipelas) with a fairly limited benefit considering some decrease in the clinical signs. Therefore, in 1998, the farm changed the vaccine to a specific AR one, containing inactivated B. bronchiseptica suspension and a purified P. multocida toxoid (vaccine B). Clinical symptoms disappeared and production performance was gradually improved. According to the results of repeated bacteriological and P. multocida toxin antibody screening examinations in the herd, toxigenic P. multocida completely disappeared, while B. bronchiseptica substantially decreased, although vaccination was stopped in 2003.
Authors conclude that eradication of AR is feasible on large farms by using a complex control programme based on an efficacious vaccine, including a continuously high level management practice and, if necessary, medication at the critical young age of the piglets.

J. Gál – G. Csécsei:
HYPOPLASY OF TAIL MUSCLE FIBERS IN A MADAGASCARIAN DAY GECKO (PHELSUMA MADAGASCARIENSIS KOCHI). CASE REPORT

While studying the background of abnormal tail posture in a Madagascarian day gecko (Phelsuma madagascariensis kochi), a well-known phenomenon to lizard keepers, the authors found hypoplasy of the tail musculature. At the tail base of the investigated specimen the connective tissue fibers between the skin and the tail musculature were normally developed and had normal structure. However, the muscle fibers of the tail were attenuated and showed an uneven staining locally, while the fibers of the longitudinal muscle bundles were partly broken up, with the sarcolemma still intact. The occasional presence of adipose tissue replacing muscle fibers was detected.
The authors suspect genetic factors resulting from inbreeding in addition to improper feeding (food with high energy and fat contents) to cause tail musculature hypoplasy.